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Updated: Jun 4, 2026
Measuring Psoriasis Severity at Home
Published on: March 1, 2024
Long-term prognosis and comorbidities associated with psoriasis in the Newfoundland and Labrador founder population
Wayne P Gulliver1, Don Macdonald, Neil Gladney
1Disciple of Medicine, Faculty of Medicine, Memorial University of Newfoundland. wgulliver@newlabresearch.com
Background:
Psoriasis is a common chronic immune-mediated inflammatory disorder of the skin with several associated comorbidities.
Objective:
To assess the prevalence of comorbidities in a cohort of psoriasis patients within the Canadian province of Newfoundland and Labrador (NL).
Methods:
This cross-sectional observational study investigated hospital-coded comorbidities associated with psoriasis in comparison to the general NL hospitalized population.
Results:
Patients died significantly younger than the general population, with patients having an earlier disease onset (≤ 25 years) dying at a younger age than those with a later onset (> 25 years; 59.3 vs 71.2; p = .001). Patients were hospitalized more frequently for several system disorders than the general population, and a potential association was observed between prognostic factors such as age at onset, disease severity, and HLA-Cw6 genotype and certain comorbid conditions.
Conclusion:
This study supports an association between psoriasis and other conditions, such as circulatory and endocrine diseases.
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