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Updated: Jun 4, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
[Retrograde intrarenal surgery (RIRS). Technical complement for cases of acute lithiasis]
1Servicio de Urología, Hospital Río Hortega, Valladolid, España. amonsesmero@yahoo.es
Retrograde intrarenal surgery (RIRS) effectively treats kidney stones, especially larger ones. Washing renal cavities during RIRS aids fragment removal, reducing the need for repeat procedures.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Nephrolithiasis Management
Context:
- Retrograde intrarenal surgery (RIRS) is a key treatment for kidney stones.
- Fragment elimination can be challenging due to stone size or renal anatomy.
- Minimally invasive techniques are preferred for renal stone management.
Purpose:
- To evaluate the efficacy of RIRS with renal cavity washing for kidney stone removal.
- To assess the impact of stone size on RIRS outcomes.
- To determine the effectiveness of a minipercutaneous sheath for fragment lavage.
Summary:
- 37 RIRS procedures were performed on 35 patients with renal lithiasis, divided into groups based on stone size (<1.5 cm and >1.5 cm).
- The study utilized flexible ureteroscopy with Holmium laser lithotripsy and fragment extraction baskets.
- In cases with significant stone burden or altered anatomy, renal cavities were washed using a mini-percutaneous sheath to aid fragment drainage.
Impact:
- RIRS demonstrated high stone-free rates at 3 months (93.1%), particularly for smaller stones.
- Renal cavity washing proved beneficial in eliminating fragments, reducing retreatment rates.
- The procedure showed no instances of ureteral stenosis, highlighting its safety profile.
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