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Construction of the eight-item patient-reported outcomes measurement information system pediatric physical function

Esi Morgan DeWitt1, Brian D Stucky, David Thissen

  • 1Department of Pediatrics, Duke University Medical Center, Durham, NC, USA. esi.morgan-dewitt@cchmc.org

Journal of Clinical Epidemiology
|February 5, 2011
PubMed

Insights

Patient-reported outcomes measurement information system (PROMIS) developed pediatric physical function (PF) item banks. These new measures effectively assess mobility and upper extremity function in children.

Area of Science:

  • Pediatric Health Measurement
  • Psychometrics
  • Patient-Reported Outcomes

Background:

  • Existing physical function (PF) measures for children often lack modern psychometric validation.
  • The Patient-Reported Outcomes Measurement Information System (PROMIS) aims to standardize outcome measurement across diverse populations.
  • Development of reliable and valid pediatric PF measures is crucial for clinical assessment and research.

Purpose of the Study:

  • To create self-report physical function (PF) measures for children using advanced psychometric methods.
  • To develop item banks and short forms for assessing pediatric mobility and upper extremity function within the PROMIS framework.

Main Methods:

  • Applied PROMIS qualitative methodology to develop item pools for mobility and upper extremity function.
  • Administered items to 3,048 children (aged 8-17 years) and analyzed data using factor analysis and differential item functioning (DIF) analysis.
  • Evaluated item dimensionality, local dependence (LD), DIF, and discrimination; simulated computerized adaptive testing (CAT) and constructed short forms.

Main Results:

  • Confirmed two dimensions of PF: mobility and upper extremity function.
  • Retained 52 of 70 items, resulting in a 23-item mobility bank and a 29-item upper extremity bank.
  • Created eight-item short forms demonstrating high information across a wide range of functioning levels.

Conclusions:

  • The PROMIS pediatric PF item banks and short forms provide valid and reliable measures of mobility and upper extremity function.
  • These measures exhibit strong psychometric properties, suitable for large-scale testing and clinical application in pediatric populations.
  • The developed tools align with PROMIS goals for standardized, high-quality patient-reported outcome measurement.
Abstract

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