A strong case for personalized, targeted cancer prevention

Marcia I Dawson1

  • 1Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA. mdawson@sanfordburnham.org

Summary

Genetic variations predict head and neck cancer recurrence. Specific genotypes in the retinoid X receptor alpha gene significantly reduced risk in patients receiving 13-cis-retinoic acid (13-cRA), advancing personalized cancer prevention.

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