Early detection of colorectal cancer: second feasibility study

The second study undertaken to test the feasibility of wide-scale controlled trial of Hemoccult® as a useful means of early detection of colorectal cancer is described. Of eight physicians recruited for this study, five completed it; 260 patients were enrolled, and randomized to obtain 152 in the study group and 108 in the control group. Of patients in the study group, 71% complied with the protocol. A third feasibility study will have to be mounted to reassess physician compliance and also to reassess the predicted rate of patient enrollment to the study.