Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Tension Response at Adherens Junctions

Tension Response at Adherens Junctions

The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin homology) domains...

Surface Tension, Capillary Action, and Viscosity

Surface Tension, Capillary Action, and Viscosity

Surface Tension
The various IMFs between identical molecules of a substance are examples of cohesive forces. The molecules within a liquid are surrounded by other molecules and are attracted equally in all directions by the cohesive forces within the liquid. However, the molecules on the surface of a liquid are attracted only by about one-half as many molecules. Because of the unbalanced molecular attractions on the surface molecules, liquids contract to form a shape that minimizes the number...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Systematic Engineering of Intra-Articular Drug Release Profiles Reveals a Key Determinant of Disease-Modifying Efficacy in Post-Traumatic Osteoarthritis.

bioRxiv : the preprint server for biology·2026

Same author

A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines.

Nature immunology·2026

Same author

Mechanical compliance enhances the impulsive energy absorption of glassy polymer films.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Unraveling the Relevant Length and Time Scales of Elastomers in a High Strain Rate Test.

Macromolecules·2026

Same author

A radically simple, ingestible colorimetric biosensor pill for cost-effective, non-invasive monitoring of intestinal inflammation.

Device·2026

Same author

A disease-severity-responsive nanoparticle enables potent ghrelin messenger RNA therapy in osteoarthritis.

Nature nanotechnology·2026

Same journal

Estimating the Segregation Strength of Microphase-Separated Diblock Copolymers from the Interfacial Width.

Journal of polymer science. Part B, Polymer physics·2024

Same journal

Effect of Adjacent Hydrophilic Polymer Thin Films on Physical Aging and Residual Stress in Thin Films of Poly(butylnorbornene-<i>ran-</i>hydroxyhexafluoroisopropyl norbornene).

Journal of polymer science. Part B, Polymer physics·2020

Same journal

Combinatorial functionalization with bisurea-peptides and antifouling bisurea additives of a supramolecular elastomeric biomaterial.

Journal of polymer science. Part B, Polymer physics·2020

Same journal

Comparing the Mechanical Response of Di-, Tri-, and Tetra-functional Resin Epoxies with Reactive Molecular Dynamics.

Journal of polymer science. Part B, Polymer physics·2019

Same journal

Salt concentration dependence of the mechanical properties of LiPF<sub>6</sub>/poly(propylene glycol) acrylate electrolyte at a graphitic carbon interface: A reactive molecular dynamics study.

Journal of polymer science. Part B, Polymer physics·2018

Same journal

Charge transport and structure in semimetallic polymers.

Journal of polymer science. Part B, Polymer physics·2017

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 4, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

A "Self-Pinning" Adhesive Based on Responsive Surface Wrinkles.

Edwin P Chan¹, Jeffrey M Karp, Robert S Langer

¹Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.

Journal of Polymer Science. Part B, Polymer Physics

|February 5, 2011

Summary

This summary is machine-generated.

Dynamically evolving surface wrinkles enhance hydrogel adhesion by controlling crack pathways. This controlled debonding, influenced by contact time, improves interfacial strength.

More Related Videos

Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots

Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots

Published on: January 13, 2023

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Published on: March 1, 2016

Related Experiment Videos

Last Updated: Jun 4, 2026

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Origami Inspired Self-assembly of Patterned and Reconfigurable Particles

Published on: February 4, 2013

Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots

Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots

Published on: January 13, 2023

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Published on: March 1, 2016

Area of Science:

Materials Science
Surface Physics
Adhesion Science

Background:

Surface wrinkles form spontaneously due to critical compressive stress and elastic instability.
Understanding wrinkle formation is key to controlling surface properties.

Purpose of the Study:

To demonstrate that dynamically changing surface wrinkles can improve interfacial adhesion with hydrogel surfaces.
To investigate the role of wrinkle morphology evolution in adhesion control.

Main Methods:

Inducing dynamic changes in surface wrinkle morphology via external stimuli.
Analyzing the effect of evolving wrinkle patterns on hydrogel debonding.
Quantifying interfacial adhesion based on crack separation pathways and contact time.

Main Results:

Dynamically evolving surface wrinkles were shown to enhance interfacial adhesion with hydrogel.
The improvement in adhesion is linked to the local pinning of crack separation pathways by wrinkles.
Debonding control and adhesion enhancement are dependent on the contact time with the hydrogel.

Conclusions:

Dynamic control of surface wrinkle morphology offers a novel strategy to enhance hydrogel adhesion.
Wrinkle-mediated pinning of crack pathways is a critical mechanism for controlled debonding.
Contact time is a crucial parameter influencing the effectiveness of wrinkle-based adhesion enhancement.