Related Experiment Video
Updated: Jun 4, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
General anesthesia with thoracic paravertebral block for modified radical mastectomy
Preeyaphan Arunakul1, Acksara Ruksa
1Department of Anesthesia, Faculty of Medicine, Thammasat University, Pathumthani, Thailand. preeyaphan@hotmail.com
Objective:
To evaluate the effect of single-injection paravertebral block (PVB) combined with general anesthesia on 24-hour postoperative morphine requirement in patients undergoing modified radical mastectomy (MRM).
Material And Method:
20 patients were randomly assigned into 2 groups. Patients in the control group were given only general anesthesia. Patients in the PVB group received 0.3 ml/kg of 0.5% plain bupivacaine at T4 paravertebral space followed by general anesthesia. Both groups received intravenous morphine patient-controlled analgesia (PCA) device postoperatively. All patients were evaluated at 1 and 24 hours for pain, nausea and vomiting. Twenty-four hour morphine consumption, antiemetics requirement, and overall satisfaction were recorded.
Results:
Patients with PVB had lower incidence and severity of postoperative pain, nausea and vomiting and other serious complications. No patients were unsatisfied with anesthetic techniques.
Conclusion:
PVB can reduce postoperative opioid requirement, pain, and severity of nausea and vomiting in MRM.
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