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Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
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Ipilimumab: a promising immunotherapy for melanoma

Jaykumar R Thumar1, Harriet M Kluger

  • 1Yale Cancer Center, Yale School of Medicine, New Haven, CT 06451, USA.

Oncology (Williston Park, N.Y.)
|February 8, 2011
PubMed
Summary

Ipilimumab, an antibody targeting cytotoxic T-lymphocyte antigen 4 (CTLA-4), demonstrated overall survival benefits in metastatic melanoma. This immune modulation therapy presents unique challenges in treatment monitoring and toxicity management.

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