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Updated: Jun 4, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Association between social isolation and left ventricular mass.

Carlos J Rodriguez¹, Mitchell S V Elkind, Lynn Clemow

¹Department of Medicine, Columbia University, New York, NY 10032, USA.

The American Journal of Medicine

|February 8, 2011

Summary

Social isolation, defined as lacking friendships, is common and linked to higher left ventricular mass, especially in Hispanic individuals. This heart condition predictor may be influenced by social connection levels.

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Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

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Published on: June 15, 2020

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Last Updated: Jun 4, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Published on: June 15, 2020

Area of Science:

Cardiology
Social Epidemiology
Public Health

Background:

Social isolation is a known risk factor for cardiovascular disease progression.
Increased left ventricular mass predicts cardiovascular morbidity and mortality.
The link between social isolation and left ventricular mass remains unclear.

Purpose of the Study:

To investigate the association between social isolation and left ventricular mass.
To determine if social isolation is a determinant of increased left ventricular mass.

Main Methods:

Cross-sectional study of 2021 Northern Manhattan Study participants without clinical cardiovascular disease.
Social isolation defined as knowing fewer than 3 people well enough to visit.
Left ventricular mass indexed to height(2.7) via echocardiograms and compared between groups.

Main Results:

13.5% of participants were socially isolated.
Socially isolated individuals had significantly higher average left ventricular mass (50.2 vs. 47.6 gm/m(2.7)).
Social isolation was significantly associated with greater left ventricular mass in Hispanics (P=.002), but not in other groups.

Conclusions:

Social isolation is prevalent in this urban tri-ethnic cohort and linked to lower socioeconomic status.
Socially isolated Hispanics demonstrated a higher risk for increased left ventricular mass.