Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiofrequency ablation produces stiffer atrial lesions than pulsed-field ablation: in vivo and ex vivo MR elastography in pigs.

Heart rhythm·2026
Same author

Brain MR Elastography Metrics Associated with Alterations in Learning and Memory in People with HIV.

Research square·2026
Same author

Multifrequency tabletop magnetic resonance elastography for ex-vivo characterization of murine intestinal tissue biomechanics.

Journal of the mechanical behavior of biomedical materials·2026
Same author

Stiffness and Tissue Viscosity in a Cerebral Neoplasm Measured by Preoperative Multifrequency Magnetic Resonance Elastography (MRE) Guide the Differential Diagnosis of Brain Tumors by Ruling Out Glioma.

Case reports in medicine·2026
Same author

Impact of severe hepatic iron overload on MR and ultrasound time-harmonic elastography.

Journal of the mechanical behavior of biomedical materials·2026
Same author

Magnetic resonance elastography for noninvasive evaluation of parotid tumors: a feasibility study.

European journal of radiology·2026
Same journal

Examination of participant sex bias in international society of biomechanics conference abstract submissions: patterns across cohorts, countries, and contexts.

Journal of biomechanics·2026
Same journal

Shear wave velocity of biceps femoris and medial gastrocnemius in different positions and intensities: a cross-sectional study in healthy young males.

Journal of biomechanics·2026
Same journal

Gait event detection using hybrid EMG/IMU systems: effect of SENIAM-constrained sensor placement on lower limb segments.

Journal of biomechanics·2026
Same journal

Relationship between knee adduction moment and knee contact forces during walking and running with modified foot progression angles.

Journal of biomechanics·2026
Same journal

Scaling contact force parameters across body size, limb count, and number of contact spheres.

Journal of biomechanics·2026
Same journal

The extrapolated body center of mass predicts subsequent foot placement choice during dynamic single-leg landings.

Journal of biomechanics·2026
See all related articles

Related Experiment Video

Updated: Jun 4, 2026

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
12:18

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

Published on: February 9, 2012

Wide-range dynamic magnetic resonance elastography.

Kerstin Riek1, Dieter Klatt, Hassan Nuzha

  • 1Department of Medical Informatics, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany.

Journal of Biomechanics
|February 8, 2011
PubMed
Summary
This summary is machine-generated.

Magnetic resonance elastography (MRE) measures tissue mechanics. This study introduces wide-range dynamic MRE for higher frequencies, revealing significant differences in fibrotic liver and muscle tissue elasticity compared to normal tissues.

More Related Videos

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography
07:57

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography

Published on: May 10, 2022

A Three-Dimensional Digital Model for Early Diagnosis of Hepatic Fibrosis Based on Magnetic Resonance Elastography
06:09

A Three-Dimensional Digital Model for Early Diagnosis of Hepatic Fibrosis Based on Magnetic Resonance Elastography

Published on: July 21, 2023

Related Experiment Videos

Last Updated: Jun 4, 2026

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
12:18

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

Published on: February 9, 2012

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography
07:57

Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography

Published on: May 10, 2022

A Three-Dimensional Digital Model for Early Diagnosis of Hepatic Fibrosis Based on Magnetic Resonance Elastography
06:09

A Three-Dimensional Digital Model for Early Diagnosis of Hepatic Fibrosis Based on Magnetic Resonance Elastography

Published on: July 21, 2023

Area of Science:

  • Biophysics
  • Medical Imaging
  • Biomaterials

Background:

  • Tissue mechanical properties are sensitive indicators of disease, detectable via elastography.
  • Human Magnetic Resonance Elastography (MRE) operates at low frequencies (<100 Hz), while small sample MRE requires higher frequencies (200-800 Hz).
  • Complex shear modulus (G*) dispersion across different frequency bands necessitates frequency-independent viscoelastic models for accurate elastography data comparison.

Purpose of the Study:

  • To present high-resolution MRE data of G* for various biological samples at high vibration frequencies (200-800 Hz).
  • To determine material constants (μ and α) of the springpot model, characterizing shear elasticity and G* dispersion.
  • To establish baseline data for understanding tissue mechanics across different MRE frequency ranges.

Main Methods:

  • High-resolution MRE was performed on agarose gel, liver, brain, and muscle samples using a 7T-animal scanner.
  • Vibration frequencies ranged from 200-800 Hz to capture wide-range dynamic MRE data.
  • The springpot model was applied to determine material constants μ (shear elasticity) and α (G* dispersion slope).

Main Results:

  • Calf brain and bovine liver exhibited similar μ and α values.
  • Fibrotic human liver (METAVIR score 3) showed ~15 times higher shear elasticity (μ) than normal liver, comparable to bovine muscle.
  • Fibrotic liver had the highest α, followed by brain and normal liver; muscle exhibited the lowest α, and gel showed minimal G* dispersion.

Conclusions:

  • The developed wide-range dynamic MRE technique enables characterization of tissue mechanics at higher frequencies.
  • Significant variations in shear elasticity and viscoelasticity were observed across different tissue types and disease states.
  • This method provides crucial baseline data for comparing human and small-sample MRE, enhancing the understanding of tissue mechanics.