A novel preparation of methyl-β-cyclodextrin from dimethyl carbonate and β-cyclodextrin
Related Experiment Video
Updated: Jun 4, 2026

Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
Published on: December 16, 2022
Yongjiang Gan1, Yimin Zhang, Chuanhao Xiao
1School of Chemical Engineering and Technology, Key Laboratory for Green Chemical Technology of State Education Ministry, Tianjin University, China.
Abstract:
A novel green synthesis process about methyl-β-cyclodextrin has been investigated through the reaction between β-cyclodextrin and dimethyl carbonate by anhydrous potassium carbonate as catalyst in DMF. The influence of experimental factors including the molar ratio of dimethyl carbonate to β-cyclodextrin, reaction temperature, and reaction time on the average degree of substitution of methyl-β-cyclodextrin was studied. The results show that the average degree of substitution of methyl-β-cyclodextrin can be dependent on the reaction temperature and the molar ratio of raw material primarily. The structures of methyl-β-cyclodextrin were characterized by TLC, IR, MS, (1)H NMR, and (13)C NMR.
More Related Videos
Related Concept Videos
Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives
Intramolecular Claisen Condensation of Dicarboxylic Esters: Dieckmann Cyclization
Alkylation of β-Diester Enolates: Malonic Ester Synthesis
Stability of Substituted Cyclohexanes
The two chair conformations of cyclohexanes undergo rapid interconversion at room temperature. Both forms have identical energies and stabilities, each comprising equal amounts of the equilibrium mixture. Replacing a hydrogen atom with a functional group makes the two conformations energetically non-equivalent.
For example, in...
Carbocations
Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction

