Related Experiment Video
Updated: Jun 4, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
[Contact dermatitis in children - a review of current opinions]
M P Castanedo-Tardan1, C Matiz, S E Jacob
1Sección de Dermatología, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Insights
Contact dermatitis is common in children, affecting them similarly to adults. Previously underestimated, pediatric cases are now recognized due to improved diagnostic methods like patch testing.
Area of Science:
- Dermatology
- Pediatric Allergy and Immunology
Background:
- Historically, contact dermatitis was considered rare in children due to perceived immature immune systems and lower allergen exposure.
- Underdiagnosis in pediatric populations was partly due to the infrequent use of appropriate diagnostic skin tests.
Purpose of the Study:
- To re-evaluate the prevalence of contact dermatitis in the pediatric population.
- To compare the incidence of contact dermatitis in children versus adults.
Main Methods:
- Review of international literature from the past decade.
- Analysis of recent US data published within the last year.
- Consideration of modified patch testing techniques for pediatric patients.
Main Results:
- Recent data indicate that contact dermatitis is a common condition in children.
- The prevalence of contact dermatitis in pediatric patients is comparable to that in adults.
- Appropriate skin testing, including modified patch testing, is crucial for diagnosis in children.
Conclusions:
- Contact dermatitis is a significant condition in pediatric populations, not merely an adult disease.
- The prevalence is similar across age groups, challenging previous assumptions.
- Updated diagnostic approaches confirm the widespread occurrence of pediatric contact dermatitis.
Abstract:
In the not so distant past, in the United States contact dermatitis was considered to be a condition that affected mainly adults. The diagnosis was certainly less often rendered in pediatrics, mainly because it was believed that a child's immune system was immature and that children were generally exposed to fewer allergens. With this in mind, we can attribute the low prevalence formerly reported for this disease partly to the fact that most affected children were not (and are still not) evaluated using appropriate skin tests. Patch testing in children requires certain modifications, but the international literature of the last decade and US data published in the past year indicate that contact dermatitis is a common condition in the pediatric population and that the prevalence is similar in children and adults.
Related Concept Videos
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Allergic Reactions
Drug Toxicity: Allergic Reactions
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Allergic Drug Reactions
Acne Infection

