[Monoclonal gammapathy of uncertain significance. A perspective from the primary care setting]

Eight cases of monoclonal gammapathy of uncertain significance are reported. They were detected from routine analysis in patients from the general population who consulted for several diseases to a primary care center. One patient developed multiple myeloma and the rest remained stable. As there is no effective method to identify which patients with monoclonal gammapathy of uncertain significance will undergo a malignant transformation, it is suggested that periodical clinical and laboratory controls are the only effective means for the monitoring of this type of patients.