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Pantoprazole induces severe acute hepatitis

C Sandig1, C Flechtenmacher, W Stremmel

  • 1Department of Gastroenterology and Hepatology, University Hospital of Heidelberg, Heidelberg, Germany. Catharina.Sandig@med.uniheidelberg.de

Zeitschrift Fur Gastroenterologie
|February 8, 2011
PubMed
Summary

Pantoprazole, a proton pump inhibitor, can cause severe acute hepatitis in patients undergoing corticosteroid therapy for encephalomyelitis disseminata. Discontinuation of pantoprazole led to patient recovery, suggesting drug-induced liver injury.

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