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Updated: Jun 4, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
[Screening and care of chronic renal insufficiency in the elderly population]
Laurent Tliba1, Bruno Le Dastumer
1Hôpital Sainte-Périne-Rossini-Chardon Lagache (AP-HP), Paris. laurent.tliba@spr.aphp.fr
Insights
Chronic renal insufficiency (CRI) is rising in elderly populations, driven by diabetes and vascular issues. Accurate assessment of glomerular filtration rate is crucial for managing this growing public health concern.
Area of Science:
- Nephrology
- Geriatrics
- Public Health
Context:
- Increasing prevalence of chronic renal insufficiency (CRI) with advancing age.
- CRI in the elderly is predominantly linked to diabetes, vascular diseases, and glomerular conditions.
- Challenges in accurately assessing glomerular filtration rate (GFR) in older adults.
Purpose:
- To highlight the growing public health challenge of CRI in the elderly.
- To identify the primary etiologies of CRI in this demographic.
- To underscore the limitations in current GFR assessment methods.
Summary:
- Chronic renal insufficiency (CRI) prevalence escalates with age, posing a significant public health issue.
- Diabetes and vascular/glomerular origins are key drivers of CRI in the elderly.
- Imprecise glomerular filtration rate assessment remains a critical limitation in managing CRI.
Impact:
- Emphasizes the need for improved diagnostic tools for GFR estimation.
- Stresses the importance of targeted interventions to slow CRI progression in older adults.
- Highlights the role of managing complications to prevent frailty in elderly patients with CRI.
Abstract:
The prevalence of chronic renal insufficiency (CRI) increases with age. This growth shall result in it becoming a public health issue for the most elderly In this age group, chronic renal insufficiency primarily stems from diabetes and vascular and glomerular origins. The limiting point is the assessment of the glomerular filtration rate which remains imprecise. Care aims to limit the development of renal insufficiency and to prevent its complications, which are sources of fragility.
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