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Predictors of crying, feeding and sleeping problems: a prospective study
G Schmid1, A Schreier, R Meyer
1Department of Psychosomatic Medicine and Psychotherapy, Klinikum rechts der Isar, Technische Universitaet, Muenchen, Germany. g.schmid@tum.de
Insights
Infant regulatory problems like crying, feeding, and sleeping issues are linked to various pre-, peri-, and post-natal factors. Identifying these predictors aids in early recognition of at-risk infants.
Area of Science:
- Pediatric Neurodevelopment
- Infant Health and Behavior
- Psychosocial Pediatrics
Background:
- Infant regulatory problems (excessive crying, feeding/sleeping difficulties) are early indicators of developmental issues.
- The precise causes of these regulatory problems remain largely unknown.
- Understanding predictors is crucial for early intervention and improved infant outcomes.
Purpose of the Study:
- To investigate pre-, peri-, and post-natal neurophysiological and psychosocial predictors.
- To identify factors associated with single and multiple infant regulatory problems.
- To analyze these predictors at 5 months of age.
Main Methods:
- Prospective longitudinal study of 5093 singleton infants born at neonatal risk.
- Data analyzed using crude and multivariate logistic regression.
- Regulatory problems assessed via standardized parental interviews by study pediatricians.
Main Results:
- 30.7% of infants experienced single or multiple regulatory problems at 5 months.
- Breastfeeding showed mixed effects: increased odds of sleeping problems, decreased odds of feeding problems.
- Very preterm birth, fetal abnormalities, family adversity, and psychosocial stress were significant predictors of regulatory problems.
Conclusions:
- Pre-, peri-, and post-natal neurophysiological and psychosocial factors significantly predict infant regulatory problems.
- These findings are valuable for the early identification of infants at risk.
- Early recognition facilitates timely interventions to mitigate adverse developmental trajectories.
Background:
Infant regulatory problems, that is, excessive crying, feeding and/or sleeping difficulties, are precursors of adverse development. However, the aetiology of regulatory problems is still unclear. The aim of this study was to investigate pre-, peri- and post-natal neurophysiological and psychosocial predictors of single and multiple regulatory problems at 5 months of age.
Methods:
This prospective longitudinal study included all children born at neonatal risk in a geographically defined area in southern Germany. The data of n = 5093 singleton infants (83.6%) were analysed using crude and multivariate logistic regression analyses. As outcome measures we used single and multiple regulatory problems, that is, crying, feeding and/or sleeping difficulties at 5 months of age, which were assessed via a standardized interview with the parents by study paediatricians as part of a neurodevelopmental examination.
Results:
In total, 30.7% of the sample suffered from single or multiple regulatory problems at 5 months. Breastfeeding increased the odds of single sleeping problems 5.12-fold, but decreased the odds of single feeding problems [odds ratio (OR) 0.51; 95% confidence interval (CI) 0.35-0.74]. Very preterm birth was predictive of single feeding (OR 1.79; 95% CI 1.25-2.55) and multiple regulatory problems (OR 2.03; 95% CI 1.19-3.46), and foetal abnormalities increased the odds of single feeding and multiple regulatory problems from 1.53- to 1.64-fold. Family adversity and psychosocial stress factors were associated with single crying and multiple regulatory problems.
Conclusions:
Pre-, peri- and post-natal neurophysiological and psychosocial factors are predictive of single and multiple regulatory problems. The results may be useful in terms of early recognition of at risk groups for regulatory problems.
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