Related Experiment Video
Updated: Jun 4, 2026

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy
Published on: September 27, 2021
Advances in oral transmucosal drug delivery
Viralkumar F Patel1, Fang Liu, Marc B Brown
1School of Pharmacy, University of Hertfordshire, Hatfield, AL10 9AB, UK.
Abstract:
The successful delivery of drugs across the oral mucosa represents a continuing challenge, as well as a great opportunity. Oral transmucosal delivery, especially buccal and sublingual delivery, has progressed far beyond the use of traditional dosage forms with novel approaches emerging continuously. This review highlights the physiological challenges as well as the advances and opportunities for buccal/sublingual drug delivery. Particular attention is given to new approaches which can extend dosage form retention time or can be engineered to deliver complex molecules such as proteins and peptides. The review will also discuss the physiology and local environment of the oral cavity in vivo and how this relates to the performance of transmucosal delivery systems.
Related Concept Videos
Oral Drug Delivery Systems: Introduction
Drug Delivery Systems: Different Types
Drug Delivery: Enteral Route
Drugs in...
Oral Drug Delivery Systems: Delayed-Release Systems
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs through the...
Oral Drug Delivery Systems: Continuous-Release Systems
