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Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

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IMRT for image-guided single vocal cord irradiation.

Sarah O S Osman¹, Eleftheria Astreinidou, Hans C J de Boer

¹Department of Radiation Oncology, Erasmus Medical Center-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands. s.osman@erasmusmc.nl

International Journal of Radiation Oncology, Biology, Physics

|February 9, 2011

Summary

Intensity-modulated radiotherapy (IMRT) for single vocal cord irradiation effectively covers the target while significantly reducing radiation dose to critical structures, potentially improving patient quality of life.

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Area of Science:

Radiation Oncology
Medical Physics
Head and Neck Cancer Treatment

Background:

Developing image-guided single vocal cord irradiation for T1a glottic carcinoma.
Conventional radiotherapy techniques may deliver suboptimal doses to organs at risk.

Purpose of the Study:

Compare dose coverage of the affected vocal cord.
Evaluate dose delivery to organs at risk.
Assess conventional, coplanar IMRT, and non-coplanar IMRT techniques.

Main Methods:

Ten patients with T1a glottic carcinoma were analyzed.
Treatment plans generated using conventional, coplanar IMRT, and non-coplanar IMRT.
Intensity-modulated radiotherapy (IMRT) plans optimized using an in-house algorithm and Monte Carlo dose calculation.

Main Results:

All techniques achieved comparable target dose coverage (67 ± 1 Gy).
Intensity-modulated radiotherapy (IMRT) significantly reduced contralateral vocal cord dose (39 ± 8 Gy coplanar, 36 ± 6 Gy non-coplanar) compared to conventional plans (66 ± 1 Gy).
IMRT demonstrated consistent dose reduction to other critical organs at risk.

Conclusions:

Single vocal cord irradiation using intensity-modulated radiotherapy (IMRT) provides excellent target coverage.
IMRT significantly spares critical structures, potentially enhancing quality of life post-treatment.
This technique holds promise for maintaining local control rates in T1a glottic carcinoma.