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[Submandibular swelling and its differential diagnosis].

I Eleftheriadis1, P Papadimitriou, H Tzelepi

  • 1Dental School, University of Thessaloniki, Greece.

To Helleniko Periodiko Gia Stomatike & Gnathoprosopike Cheirourgike
|June 1, 1990
PubMed
Summary

Submandibular swelling can stem from various non-cancerous conditions like infections or autoimmune disorders. However, asymmetric enlargement, particularly in older adults, often indicates metastatic disease requiring investigation of primary cancer sites.

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Area of Science:

  • Head and Neck Surgery
  • Otolaryngology
  • Oncology

Context:

  • Submandibular lumps are common, with diverse etiologies ranging from infections and autoimmune conditions to neoplastic growths.
  • Differential diagnosis is crucial, as submandibular lymphadenopathy can arise from local infections or systemic diseases.

Purpose:

  • To present representative cases of submandibular swelling.
  • To highlight the differential diagnosis of submandibular masses, emphasizing the importance of ruling out malignancy.

Summary:

  • Nonmalignant causes include mumps, sialadenitis, Sjögren syndrome, cysts, and infections (e.g., dental, respiratory, mononucleosis).
  • Neoplastic causes involve submandibular gland tumors, parotid gland tail tumors, Hodgkin's disease, and non-Hodgkin's lymphomas.

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  • Metastatic disease is a primary concern for asymmetric submandibular enlargement in individuals over 40, necessitating a thorough search for head, face, and oral cavity primary tumors.

    • Impact:

    • This review aids clinicians in systematically evaluating submandibular swellings.
    • It underscores the critical need to consider metastatic disease in the differential diagnosis, potentially leading to earlier cancer detection and improved patient outcomes.