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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
Systemic lupus erythematosus presenting as ischaemic proctitis.
P Chattopadhyay1, C Abby Philips, D Dhua
1Department of Medicine, Nil Ratan Sircar Medical College, 138 AJC Bose Road, Kolkata 700 014, West Bengal, India. drpartha73@gmail
Lupus
|February 9, 2011
Summary
Ischaemic proctitis is a rare manifestation of systemic lupus erythematosus (SLE). Early diagnosis and aggressive steroid treatment led to significant improvement in a patient presenting with rectal bleeding due to SLE.
Area of Science:
- Gastroenterology
- Rheumatology
- Internal Medicine
Background:
- Ischaemic colitis is a rare complication of systemic lupus erythematosus (SLE).
- High SLE activity is often associated with vasculitis affecting the gastrointestinal tract.
- Ischaemic proctitis with rectal ulceration as an initial SLE presentation is exceptionally rare.
Observation:
- A 38-year-old woman presented with haematochezia.
- The cause was identified as ischaemic proctitis with a large rectal ulcer.
- The patient was subsequently diagnosed with systemic lupus erythematosus (SLE).
Findings:
- The patient's condition significantly improved with systemic steroid therapy.
- This case highlights the potential for gastrointestinal manifestations in SLE.
- Aggressive management of SLE-associated vasculitis is crucial.
Implications:
- This case expands the understanding of rare SLE manifestations.
- It underscores the importance of considering SLE in patients with unexplained ischaemic proctitis.
- Effective management strategies for SLE-related gastrointestinal complications can be inferred.
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