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Acute hemolysis following iodine tincture ingestion
Yan-Chiao Mao1, Wei-Jen Tsai, Ming-Ling Wu
1Division of Clinical Toxicology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Human & Experimental Toxicology
|February 9, 2011
Summary
Iodine tincture ingestion can cause severe hemolysis and acute kidney injury. Prompt supportive care, plasma exchange, and hemodialysis led to complete recovery in an unusual case.
Area of Science:
- Toxicology
- Internal Medicine
- Emergency Medicine
Background:
- Iodine tincture is a common topical antiseptic.
- Poisoning from iodine antiseptics is rare, with reported effects including topical irritation and systemic injury.
Observation:
- An unusual case of intentional iodine tincture ingestion (60 mg/ml iodine, 40 mg/ml potassium iodide in 70% ethanol) was reported.
- The patient presented with severe hemolysis and acute renal failure.
Findings:
- The patient experienced significant hemolysis and acute kidney injury following ingestion.
- Recovery was achieved after 8 weeks of comprehensive treatment.
Implications:
- This case highlights the potential for severe systemic toxicity from intentional iodine tincture overdose.
- Highlights the importance of prompt and aggressive management including supportive care, plasma exchange, and hemodialysis for severe iodine poisoning.
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