[Central giant cell granuloma of the maxilla]

We report the experience of the clinical, histologic and radiologic features of a giant cell granuloma of the maxilla of severe growth. The removal of the lesion led to a large defect of the maxilla with oroantral fistula, which was immediately repaired by the use of the temporalis muscle flap. A four year follow-up period revealed no evidence of recurrence as well as excellent aesthetic and functional results. Further diagnostic and therapeutic problems are discussed in relation with recent literature.