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Small Bowel Transplantation In Mice
Published on: August 20, 2007
Liver transplantation: A new risk factor for intestinal intussusceptions
Sven Pischke1, Wursthorn Karsten, Johannes Hadem
1Hannover Medical School, Gastroenterology, Hepatology and Endocrinology, Germany. pischke.sven@mh-hannover.de
Annals of Hepatology
|February 9, 2011
Summary
Adult intestinal intussusception is often idiopathic. This study identifies liver transplantation, especially with hepaticojejunostomy, as a significant new risk factor for this condition.
Area of Science:
- Gastroenterology
- Abdominal Surgery
- Diagnostic Imaging
Background:
- Intestinal intussusception in adults is frequently of unknown origin.
- Known associations include inflammatory bowel disease, celiac disease, abdominal tumors, and prior surgery.
Purpose of the Study:
- To evaluate the circumstances surrounding adult intussusception.
- To identify novel risk factors for intestinal intussusception.
Main Methods:
- Retrospective analysis of 65,928 abdominal ultrasound examinations.
- Identified 32 cases of sonographically proven intussusception.
- Analyzed patient characteristics and sonographic findings.
Main Results:
- 32 cases of intussusception identified (mean age 45).
- 12 patients (38%) had prior abdominal surgery, including 8 liver transplant recipients.
- Liver transplant patients were significantly overrepresented (25% vs. 8%, p=0.0023).
Conclusions:
- Liver transplantation is a newly identified major risk factor for intestinal intussusception.
- Hepaticojejunostomy following liver transplantation appears particularly associated.
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