Manning up for men's mental illness
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Updated: Jun 4, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice
Published on: January 24, 2025
John Ogrodniczuk1, John Oliffe
1Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada. ogrodnic@interchange.ubc.ca
Abstract:
Depression is often positioned as a woman's disease, in part due to the recognition of a lower incidence of depression among men compared to women. However, downstream indicators including men's self harm and suicide suggest that depression may be less often diagnosed because men tend to deny illness, self monitor and treat symptoms, and avoid health services or have difficulty engaging care providers. As a result, men's depression, including how to identify and treat it, is poorly understood. This case study highlights some of the more common features of depression in men.
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