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Updated: Jun 4, 2026

Localization of the Locus Coeruleus in the Mouse Brain
Published on: March 7, 2019
Location of theSas-1 locus on mouse chromosome 1
D L Rosenstreich1, M G Groves, H A Hoffman
1Laboratory of Microbiology and Immunology, National Institute of Dental Research, 20014, Bethesda, Maryland.
Abstract:
Using three sets of recombinant inbred strains (BXD, BXH, and BXJ), we found the locus controlling an antigenic substance (Sas}-1) in murine serum to be closely linked to the Chromosome-1 marker,Dip-1. This linkage was confirmed by an analysis of backcross linkage. The BXD and backcross data suggest that the gene order isId-1-Dip-1-Sas-1-Mls. Data from the three sets of RI strains and the 32 backcross mice lead to the estimate that the recombination frequency betweenDip-1 andSas-1 is 0.030 ±0.015.

