Snake bites in Moyen Chari district, Chad: a five-year experience
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Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications
Published on: June 29, 2020
Enrico Rino Bregani1, Tommaso Maraffi, Tu Van Tien
1Emergency Medicine Division, Fondazione IRCCS Ca' Granda-Ospedale Policlinico, Milan, Italy. rino_bregani@yahoo.it
Insights
Snake bites pose a significant public health threat in Africa, with Echis ocellatus being a primary cause. Antivenom immunotherapy is crucial for treating envenomation, though outcomes varied with different sera.
Area of Science:
- Medical Research
- Public Health
- Tropical Medicine
Background:
- Snake bites represent a critical public health issue in Africa, leading to substantial morbidity and mortality.
- Echis ocellatus is identified as the predominant species responsible for envenomation cases across West Africa.
- Antivenom immunotherapy remains the sole specific treatment for patients suffering from snake envenomation.
Observation:
- A survey at Goundi Hospital, Chad, from 1997-2001 included 325 snake bite patients.
- Analysis focused on envenomation rates, demographics, seasonality, lethality, hospital stay, and clotting time recovery.
- Young males constituted the most frequently affected demographic group.
Findings:
- Out of 325 patients, 298 showed signs of envenomation and received antivenom treatment.
- The overall lethality rate was recorded at 8%.
- Significant differences in lethality and hospital stay duration were observed among patients treated with different antivenom sera.
Implications:
- Findings align with data from other sub-Saharan countries regarding snake bite epidemiology.
- A higher percentage of snake bite victims were admitted to the hospital in this series compared to other regions.
- The study highlights the need for effective antivenom strategies and improved hospital admission protocols for snake bite management.
Abstract:
Snake bites are of major public health importance in Africa as a cause of morbidity and mortality. Echis ocellatus is responsible for the majority of envenomation cases in West Africa. Antivenom immunotherapy is the only specific treatment available for envenomed patients. From January 1997 to December 2001, 325 patients suffering from snake bites were enrolled in a survey undertaken at Goundi Hospital, Chad. We analysed the percentage of envenomed patients, sex distribution, distribution along the year, lethality, hospital stay and recovery clotting time. Two hundred and ninety-eight patients showed signs of envenomation and were treated with antivenom immunotherapy with three different sera in consecutive periods. Young males were more frequently involved. The overall lethality was 8%. Lethality and hospital stay were significantly different in the differently treated patients. Most of the data in our series were similar to those from other sub-Saharan countries but, overall, the percentage of snake bite victims who were admitted to hospital was higher.
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