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Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations
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Integrating pharmacogenetics into gemcitabine dosing--time for a change?

Joseph Ciccolini1, Cédric Mercier, Laetitia Dahan

  • 1Pôle Oncologie, La Timone University Hospital of Marseille, 267 Rue St Pierre, 13385 Marseille, France.

Nature Reviews. Clinical Oncology
|February 10, 2011
PubMed
Summary

Identifying biomarkers for gemcitabine therapy is crucial for improving anticancer drug efficacy and reducing toxic effects. Pharmacogenetic testing, focusing on enzymes like cytidine deaminase, can personalize treatment and enhance patient care.

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