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Related Experiment Video

Updated: Jun 4, 2026

Cultivating Ex Vivo Patient-Derived Glioma Organoids Using a Tissue Chopper
05:45

Cultivating Ex Vivo Patient-Derived Glioma Organoids Using a Tissue Chopper

Published on: January 19, 2024

[High-grade gliomas in adults].

Anette Storstein1, Eirik Helseth, Tom Børge Johannesen

  • 1Nevrologisk avdeling, Haukeland universitetssykehus, Seksjon for nevrologiInstitutt for klinisk medisin, Universitetet i Bergen, Bergen. astt@helse-bergen.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|February 10, 2011
PubMed
Summary

High-grade gliomas are aggressive brain tumors with poor prognoses, despite standard treatments like surgery, radiation, and chemotherapy. Early diagnosis and multidisciplinary care are crucial for managing these complex neurological conditions.

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Area of Science:

  • Neuro-oncology
  • Malignant Brain Tumors
  • Neurological Disorders

Context:

  • High-grade glioma affects approximately 200 Norwegian patients annually.
  • Diagnosis and treatment strategies for adult high-grade gliomas are reviewed.
  • Current literature and clinical experience inform this review.

Purpose:

  • To review the diagnosis and treatment of adult high-grade gliomas.
  • To highlight key symptoms and diagnostic methods.
  • To discuss current therapeutic approaches and survival rates.

Summary:

  • Common symptoms include focal neurological deficits, seizures, and pressure symptoms.
  • Diagnosis involves magnetic resonance (MR) imaging and biopsy.
  • Standard treatment includes surgical resection, radiation, and temozolomide chemotherapy, with a 5-year survival rate of 6.1%.

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Last Updated: Jun 4, 2026

Cultivating Ex Vivo Patient-Derived Glioma Organoids Using a Tissue Chopper
05:45

Cultivating Ex Vivo Patient-Derived Glioma Organoids Using a Tissue Chopper

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Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
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Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells

Published on: November 28, 2015

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
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Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

Impact:

  • Emphasizes the composite nature of diagnosis, involving neurological and cognitive symptoms.
  • Underscores the need for effective patient communication and interdisciplinary collaboration.
  • Highlights the necessity of symptomatic management and multidisciplinary follow-up for high-grade glioma patients.