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Complete genome sequence of Brachybacterium faecium type strain (Schefferle 6-10)
Standards in Genomic Sciences
|February 10, 2011
Summary
This study presents the first complete genome sequence for Brachybacterium faecium, a bacterium notable for its unique growth cycle and uric acid degradation. This provides crucial insights into the Dermabacteraceae family within Actinobacteria.
Area of Science:
- Microbiology
- Genomics
- Actinobacteria
Background:
- Brachybacterium faecium is the type species of its genus and belongs to the phylogenetically isolated Dermabacteraceae family.
- This bacterium exhibits a distinctive rod-coccus growth cycle and possesses the capability to degrade uric acid.
- It is a Gram-positive, nonmotile bacterium that can grow under aerobic or weakly anaerobic conditions.
Purpose of the Study:
- To describe the features of Brachybacterium faecium.
- To provide the first complete genome sequence and annotation for a member of the Dermabacteraceae family.
- To contribute to the Genomic Encyclopedia of Bacteria and Archaea project.
Main Methods:
- Isolation and characterization of a Brachybacterium faecium strain from poultry deep litter.
- Whole-genome sequencing of the Brachybacterium faecium isolate.
- Bioinformatic analysis for genome annotation, including identification of protein-coding and RNA genes.
Main Results:
- The complete genome sequence of Brachybacterium faecium was determined.
- The genome is a single replicon measuring 3,614,992 bp.
- The genome contains 3129 protein-coding genes and 69 RNA genes.
Conclusions:
- This work represents the first complete genome sequence of a Dermabacteraceae family member.
- The genome sequence provides a valuable resource for understanding the biology and evolution of this bacterial family.
- The findings enhance the genomic database for Actinobacteria and contribute to the broader understanding of microbial diversity.
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