Related Experiment Video
Updated: Jun 4, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Long Term Follow up of 'Coronary Mimic Syndrome'
This study followed 22 women with chest pain and normal coronary angiograms for nearly five years. Most patients experienced no significant long-term cardiac events, suggesting reassurance is a viable treatment for this condition.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Chest pain is a common symptom with diverse etiologies.
- Normal coronary artery angiograms in patients with chest pain present a diagnostic challenge.
Purpose of the Study:
- To evaluate the long-term prognosis of female patients presenting with chest pain and normal coronary angiograms.
- To assess the efficacy of reassurance as a primary treatment modality in this cohort.
Main Methods:
- A cohort of 22 female patients with chest pain and normal coronary angiograms was prospectively followed.
- Data collection included clinical status and cardiac event monitoring over a mean follow-up period of 56 months.
- Treatment primarily involved patient reassurance.
Main Results:
- The study followed 22 women (mean age 42.3 years) with chest pain and normal coronary angiograms.
- The mean follow-up period was 56 months.
- Long-term follow-up data indicated a generally favorable prognosis with reassurance as the main intervention.
Conclusions:
- Female patients with chest pain and normal coronary angiograms exhibit a favorable long-term outlook.
- Reassurance appears to be an effective management strategy for this patient group, minimizing the need for invasive interventions.
Related Concept Videos
Acute Coronary Syndrome III: Diagnostic Studies
Coronary Artery Disease V: Interprofessional Care
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease II: Pathophysiology
Acute Coronary Syndrome IV: Interprofessional Care
