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Updated: Jun 4, 2026

Merkel Cell Polyomavirus Infection and Detection

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

Merkel cell carcinoma: case report.

Nela Sustić¹, Darko Biljan, Zelimir Orkić

¹Department of Dermatovenerology, Clinical Hospital Osijek, Osijek, Croatia. sustic.nela@kbo.hr

Collegium Antropologicum

|February 10, 2011

Summary

Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer with high mortality. Early biopsy of suspicious lesions is crucial for timely diagnosis and treatment of this dangerous neuroendocrine carcinoma.

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Area of Science:

Oncology
Dermatology
Pathology

Background:

Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine skin cancer.
MCC incidence has tripled between 1986 and 2001, with higher mortality than melanoma.
Tumors typically appear on sun-exposed skin, commonly on the head and neck.

Observation:

A case of a 70-year-old female patient presenting with a painless, red nodule on her left forearm is described.
The lesion measured 2 x 2 x 2 cm.
Surgical excision with clear margins was performed, and histopathology confirmed MCC.

Findings:

Pathohistological analysis confirmed Merkel cell carcinoma.
Sentinel lymph node biopsy results were negative, indicating no apparent spread to nearby lymph nodes.

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Last Updated: Jun 4, 2026

Merkel Cell Polyomavirus Infection and Detection

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

Implications:

Given MCC's aggressive nature and high fatality rate, prompt biopsy of any suspicious skin lesion is essential.
Early detection and diagnosis are critical for improving patient outcomes in Merkel cell carcinoma cases.