Related Experiment Video
Updated: Jun 4, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Cutaneous malignant melanoma among white Hispanics and non-Hispanics in the United States
Ray M Merrill1, Nelson D Pace, Ashley N Elison
1Department of Health Science, College of Life Sciences, Brigham Young University, 229-A Richards Building, Provo, Utah 84602, USA. Ray_Merrill@byu.edu
Aim:
To explore whether disparities exist in melanoma incidence and prognosis between White Hispanics and White non-Hispanics.
Methods:
Analyses were based on 42,770 patients with malignant melanoma in the United States, 2004 through 2006.
Results:
Hispanics were significantly less likely to be diagnosed with superficial spreading melanoma or Hutchinson's melanotic freckle, but significantly more likely to be diagnosed with nodular melanoma or acral lentiginous melanoma. Hispanics were also significantly less likely to have multiple primary cancers and less likely to receive surgical treatment. Among those diagnosed during the study period, 12.4% (n = 142) of Hispanic patients and 8.5% (n = 3,235) of non-Hispanic patients died sometime during these years. Approximately 7.3% of Hispanic patients and 4.8% of non-Hispanic patients died specifically from melanoma. Later stage at diagnosis was the primary explanation for the difference in death from melanoma between Hispanic and non-Hispanic Whites.
Conclusions:
Hispanic melanoma patients experience significantly poorer prognostic findings at diagnosis. The disparity in melanoma stage, tumor depth, and ulcerated tumors at diagnosis emphasizes the need for greater secondary prevention efforts among this group.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Pigmentation
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

