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Updated: Jun 4, 2026
26:48
Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
Acute disseminated encephalomyelitis following herpes simplex encephalitis
F El Ouni1, S Hassayoun, M Gaha
1Radiology Department, Sahloul University Hospital, Sousse, Tunisia. elounichedia@yahoo.fr
Acta Neurologica Belgica
|February 11, 2011
Summary
Acute disseminated encephalomyelitis (ADEM) is a rare neurological disorder that can occur after herpes simplex encephalitis. This case highlights MRI
Area of Science:
- Neuroimmunology
- Pediatric Neurology
- Demyelinating Diseases
Background:
- Acute disseminated encephalomyelitis (ADEM) is an immune-mediated demyelinating disorder of the central nervous system, typically affecting children and adolescents.
- ADEM often follows infections or vaccinations, but its occurrence after herpes simplex encephalitis (HSE) is uncommon.
Observation:
- A rare case of ADEM developed in a 2-year-old girl following HSE.
- The patient presented with rapid-onset, multifocal neurological deficits.
Findings:
- Magnetic resonance imaging (MRI) features were crucial in diagnosing ADEM in this patient.
- The case underscores the diagnostic utility of MRI in identifying ADEM post-HSE.
Implications:
- Recognizing ADEM in the context of HSE is vital for timely diagnosis and management.
- This case emphasizes the importance of considering ADEM in pediatric patients with neurological deterioration after HSE, guided by MRI findings.
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