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Updated: Aug 11, 2026

Biochemical Titration of Glycogen In vitro
Published on: November 24, 2013
Plasma aldosterone concentration during hypoxia, stimulated hyperglycaemia and when protein synthesis is blocked with
G Ilieva1, A Tolekova, A Logofetov
1Department ol Physiology, Higher Medical Institute, Stara Zagora.
Abstract:
In order to study the effect of various agents on aldosterone secretion, the aldosterone concentration was determined radioimmunologically in 41 rats divided in groups: group I--7 rats--controls; group II--11 rats loaded p.o. with 5.5% glucose solution in doses of 2.4 ml/100 g body weight, taking the blood sample 2 hours after the loading; group III--7 rats subjected to the same treatment, but the blood was taken 6 hours later; group IV--7 rats subjected to hypobaric hypoxy for 2 hours; group V--9 rats treated with 40 ug/100 g b. w. actinomycin D and then subjected to hypoxy for 2 hours. The blood sample from the last two groups was taken 3 hours after the end of the hypoxy. The radioimmunological determination was made using a kit of the firm Sorin--Biomedica. The results show that glucose and hypoxy act as stimulators of aldosterone secretion.
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