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Updated: Jun 4, 2026

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Quasi-continuous autodriven system with multiple rates for distraction osteogenesis
Li Wu Zheng1, Martin C M Wong, Lim Kwong Cheung
1The University of Hong Kong, Hong Kong SAR, China.
Introduction:
For a given rate of distraction a greater frequency of distraction improves bone formation. However, the current distractors used in clinic are activated manually and produces intermittent advancement.
Method:
The authors developed an automatic driver that is capable of producing quasi-continuous distraction at a set of rates of 0.5, 1.0, 1.5, 2.0, 2.5, and 3.0 mm/d. Using a customized in vitro experimental system, the function and stability of the autodriven system were tested during loading.
Results:
The angular displacement of the automatic driver was quite regular while driving a constant torque of 4.268 × 10-(3) kg m. The driving achieved the target speed with the constant torque.
Conclusions:
The automatic driven system provides a useful tool to assess the tissue healing at variable distraction rates with quasi-continuous traction. It demonstrates a potential for clinical application to shorten the treatment course of distraction osteogenesis.
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