Related Experiment Video
Updated: Jun 4, 2026

Development of a Neonatal Rat Model for Brachial Plexus Birth Injury
Published on: March 27, 2026
EMG and MRI are independently related to shoulder external rotation function in neonatal brachial plexus palsy
Robert J Talbert1, Linda J Michaud, Charles T Mehlman
1Division of Pediatric Orthopaedics, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, MLC 2017, Cincinnati, OH 45229, USA.
Insights
Electromyography (EMG) and MRI of the infraspinatus muscle can help assess shoulder function in neonatal brachial plexus palsy (NBPP). These tests, combined with clinical evaluation, improve diagnosis and treatment guidance for NBPP patients.
Area of Science:
- Orthopedics
- Neurology
- Radiology
- Physical Medicine and Rehabilitation
Background:
- Limited research exists on using electromyography (EMG) and volumetric magnetic resonance imaging (MRI) of the infraspinatus muscle to assess active global shoulder external rotation (GER) in neonatal brachial plexus palsy (NBPP).
- Physical assessment of active GER in NBPP patients can be complemented by electrophysiological and imaging techniques.
- Understanding the infraspinatus muscle's role is crucial for evaluating shoulder dysfunction in NBPP.
Purpose of the Study:
- To evaluate the relationship between EMG and MRI findings of the infraspinatus muscle and active GER in NBPP patients.
- To determine if infraspinatus muscle EMG interference patterns and MRI volume correlate with active GER outcomes.
- To assess the utility of integrating EMG and MRI with clinical assessment for NBPP.
Main Methods:
- A diagnostic study (Level II evidence) included 74 NBPP patients (age range: 1y1m to 13y3m).
- Evaluations included physical examination of the shoulder, EMG of the infraspinatus muscle, and shoulder MRI.
- Active GER was dichotomized (poor <0°, good ≥0°). EMG interference patterns were graded (≤4 poor, ≥5 good). Infraspinatus muscle volume was measured via MRI.
Main Results:
- A poor EMG interference pattern in the infraspinatus muscle was significantly associated with poor active GER (odds ratio=7.391, P=0.0022).
- Decreased infraspinatus muscle volume on MRI was also significantly related to poorer active GER (odds ratio=1.094 per % decrease, P=0.0413).
- Both EMG interference pattern and muscle volume showed significant correlations with the Mallet Score for active GER.
Conclusions:
- Infraspinatus muscle EMG interference patterns and MRI volume are strongly related to active GER, as assessed by the Mallet Score.
- Integrating clinical assessment with electrophysiological (EMG) and imaging (MRI) findings can enhance diagnostic accuracy for shoulder dysfunction in NBPP.
- These combined findings may improve guidance for selecting patient-specific interventions for NBPP.
Background:
Few studies exist with regard to the ability of electromyography (EMG) and volumetric magnetic resonance imaging (MRI) of the infraspinatus muscle to complement the physical assessment of active global shoulder external rotation (GER) in the neonatal brachial plexus palsy (NBPP) population. Therefore, the purpose of this study was to evaluate the relationships of EMG and MRI with active GER based on analysis of the infraspinatus muscle.
Methods:
Seventy-four NBPP patients (mean age, 5 y 1 m; range, 1 y 1 m to 13 y 3 m) who had undergone physical examination of the shoulder, EMG evaluation of the infraspinatus muscle, and shoulder MRI were included in this study. The outcome variable active GER was dichotomized into <0 degree active GER (poor) and ≥0 degree active GER (good). The interference pattern on EMG of the infraspinatus muscle was graded on a 6-point scale and dichotomized into ≤4 and ≥5. On shoulder MRI, infraspinatus muscle volume was measured. The infraspinatus muscle interference pattern and volume were compared with active GER.
Results:
Interference pattern on EMG of the infraspinatus muscle was significantly related to the Mallet Score (P=0.0022), with a poor interference pattern associated with an approximately 7 times higher likelihood [odds ratio=7.391; 95% confidence interval (2.054, 26.588)] of poor active GER. Infraspinatus muscle volume decrease on MRI was also significantly related to active GER (P=0.0413), with each percent volume decrease corresponding to an increase of 0.094 in the odds of having a poor Mallet Score for active GER [odds ratio=1.094; 95% confidence interval (1.004, 1.193)].
Conclusions:
The interference pattern of the infraspinatus muscle on EMG and the infraspinatus muscle volume on MRI are strongly related to active GER as assessed by the Mallet Score. Integrating clinical assessment with electrophysiological and imaging findings may improve the accuracy in evaluating shoulder dysfunction in NBPP and provide improved guidance in selecting interventions specific to the patient's pattern of deficits.
Level Of Evidence:
Diagnostic study, level II.
More Related Videos
Related Concept Videos
Spinal Nerves: Plexus I
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
Magnetic Resonance Imaging

