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Updated: Jun 4, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Childhood pustular psoriasis: case report
Yuri Nogueira Chaves1, Dulceane Natyara Cardoso, Priscila F Landulfo Jorge
1Dermatology Service, Professor Edgar Santos University Hospital Complex, The Federal University of Bahia, Salvador, BA, Brazil.
Anais Brasileiros De Dermatologia
|February 11, 2011
Summary
Generalized pustulous psoriasis (GPP) is a rare, severe skin condition. Dapsone demonstrated safe and effective treatment in an infant with GPP, offering a potential therapeutic option.
Area of Science:
- Dermatology
- Pediatrics
- Pharmacology
Background:
- Generalized pustulous psoriasis (GPP), also known as Von Zumbusch psoriasis, is a rare and severe dermatological condition.
- While GPP often presents more benignly in children, severe forms can be life-threatening.
- Current therapeutic options for GPP lack consistent efficacy and safety, particularly in infants.
Observation:
- This report details a severe case of GPP in an infant.
- The infant experienced a serious manifestation of the disease.
Findings:
- Dapsone treatment resulted in a satisfactory clinical response.
- The infant exhibited good tolerance to dapsone therapy.
Implications:
- Dapsone may represent a viable and safe treatment option for GPP in infants.
- Further research is warranted to explore dapsone's efficacy and safety profile in pediatric GPP management.
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