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Updated: Jun 4, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Case for diagnosis. Mycosis fungoides
Jonas Ribas1, Antonio Pedro Mendes Schettini, Carla Barros da Rocha Ribas
1Department of Dermatology, School of Medicine, Federal University of Amazonas, Manaus, Brazil.
Abstract:
An 18-year old female patient presented with a single, erythematous, desquamative plaque. The clearly outlined lesion was situated in the abdominal region. The patient reported that it had been present for the past year and that she had used no previous medication. Histopathology showed lymphocytic infiltration with atypia, principally affecting the superficial dermis with epidermotropism and mild spongiosis. Immunophenotyping revealed a predominance of CD3-positive cells, confirming the diagnosis of mycosis fungoides.
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