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Thyroid function in anemic fetuses

J G Thorpe-Beeston1, K H Nicolaides, R J Snijders

  • 1Harris Birthright Research Centre for Fetal Medicine, Department of Obstetrics and Gynaecology, King's College School of Medicine and Dentistry, London, UK.

Thyroid function was studied in 75 fetal blood samples obtained by cordocentesis from red cell isoimmunized pregnancies at 18-37 weeks of gestation. Thyroid-stimulating hormone (TSH), and free and total thyroxine and triiodothyronine were significantly higher than in normal controls. Furthermore, there was a significant association between the increase in TSH and the degree of fetal anemia.

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