Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Sexually Transmitted Infections

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...

Retrovirus Life Cycles

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Genital Herpes

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...

Cryptococcal Meningitis

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Distinct immune responses to HIV and CMV in Hofbauer cells across gestation highlight evolving placental immune dynamics.

Frontiers in immunology·2026

Same author

Effect of Opt-Out HIV Testing for Adolescent Patients on a Pediatric Hospital Medicine Service.

Hospital pediatrics·2026

Same author

CircRNA profiles of extracellular vesicle-enriched fractions from ART suppressed pregnant women living with HIV identifies interactome networks key to inflammation and viral latency.

Journal of translational medicine·2026

Same author

Six-Month Outcomes in Children With COVID-19 or Multisystem Inflammatory Syndrome in Children.

Hospital pediatrics·2026

Same author

Placental biology links genetic, epigenetic, ancestral, and social determinants to maternal-fetal health inequities.

Frontiers in reproductive health·2026

Same author

Hemoglobin alpha-like subunit mu is expressed during ontogeny and is elevated in alpha thalassemia.

Blood. Red cells & iron·2026

Search research articles

Related Experiment Video

Updated: Jun 4, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Published on: December 3, 2019

The HIV-Infected Adolescent.

Allison C Ross¹, Andres Camacho-Gonzalez, Sheryl Henderson

¹Pediatric Infectious Diseases, Emory University School of Medicine, 2015 Uppergate Drive, NE, Atlanta, GA, 30322, USA, across3@emory.edu.

Current Infectious Disease Reports

|February 11, 2011

Summary

Adolescents with HIV require specialized care, addressing challenges like adherence and mental health. A multidisciplinary approach improves health outcomes and transitions to adult care for HIV-positive youth.

More Related Videos

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Published on: January 31, 2020

Related Experiment Videos

Last Updated: Jun 4, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models

Published on: December 3, 2019

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Published on: January 31, 2020

Area of Science:

Pediatrics
Infectious Diseases
Adolescent Medicine

Background:

Adolescents with HIV are a diverse group with unique medical and psychosocial needs.
Both perinatally and behaviorally infected adolescents face challenges including medication nonadherence, risky sexual behaviors, and mental health issues.
Culturally sensitive, population-specific care is crucial for optimizing health outcomes.

Purpose of the Study:

To highlight the distinct and shared challenges faced by HIV-infected adolescents.
To emphasize the importance of a tailored, culturally sensitive approach to HIV care in this population.
To advocate for multidisciplinary programs to improve the transition to adult HIV care.

Main Methods:

This study is a review of current approaches and challenges in adolescent HIV care.
It synthesizes information on therapeutic needs, psychosocial stressors, and psychiatric comorbidities.
Focuses on harm reduction strategies and the transition to adult care.

Main Results:

HIV-infected adolescents exhibit diverse needs based on infection origin (perinatal vs. behavioral).
Common difficulties include poor medication adherence, high-risk sexual behaviors, psychosocial stressors, and psychiatric disorders.
Harm reduction and culturally sensitive care are vital for managing HIV in adolescents.

Conclusions:

Specialized, multidisciplinary programs are essential for addressing the complex needs of HIV-infected adolescents.
Effective care requires a population-specific, culturally sensitive approach focusing on adherence, sexual health, and mental well-being.
Improved transition to adult care programs can enhance long-term health for these individuals.