Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
Genetic Material01:20

Genetic Material

Within the human body, a complex and detailed system of trillions of cells works in unison to sustain life. Each cell houses a nucleus, which contains 46 chromosomes divided into 23 pairs. Chromosomes are highly coiled structures made of the genetic material DNA. These chromosomes are essential carriers of genetic information, with half inherited from the mother through her egg and the other half from the father's sperm, combining to create the unique genetic makeup of an individual.
Inheritance01:25

Inheritance

Gregor Mendel's pioneering work on the principles of inheritance fundamentally transformed our understanding of how traits are transmitted from generation to generation. His experiments with pea plants laid the groundwork for the discovery of genes, discrete units within organisms that control heredity.
Each gene exists in pairs, and the combination of these genes from both parents forms an individual's genotype. This genotype is a blueprint of potential traits. Examples of genotype traits...
Pharmacogenetics and Pharmacogenomics: Overview01:29

Pharmacogenetics and Pharmacogenomics: Overview

Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamics of Fear-Generalization Processes and Their Predictive Value for the Development of Anxiety-Related Psychopathology in Adolescents and Adults: A Study Protocol for a Longitudinal Study.

International journal of methods in psychiatric research·2026
Same author

Risperidone Serum Levels in Depression: Insights From a Retrospective Therapeutic Drug Monitoring Study.

Therapeutic drug monitoring·2026
Same author

Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2026 - Pharmacokinetic, pharmacogenetic and clinical aspects.

Pharmacopsychiatry·2026
Same author

[Rare genetic diseases with frequent mental symptoms].

Der Nervenarzt·2026
Same author

Preliminary Evidence for Sex Differences in CYP2C19 Metabolic Capacity During Psychotropic Drug Treatment.

Genes·2026
Same author

[Depression and parenthood - a nationwide cross-sectional study on psychoeducational services in adult psychiatry].

Psychiatrische Praxis·2026

Related Experiment Video

Updated: Jun 4, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

Genetics.

Katharina Domschke1, Jürgen Deckert

  • 1Department of Psychiatry, University of Münster, Albert-Schweitzer-Strasse 11, 48149, Münster, Germany. katharina.domschke@ukmuenster.de

Current Topics in Behavioral Neurosciences
|February 11, 2011
PubMed
Summary

Genetic factors significantly influence anxiety disorders, particularly panic disorder. Research highlights key genes in neurotransmitter systems and explores gene-environment interactions and imaging genetics for a multifactorial understanding.

Area of Science:

  • Neuroscience
  • Genetics
  • Psychiatry

Background:

  • Anxiety disorders are complex, multifactorial conditions.
  • Genetic factors play a pivotal role in their pathophysiology.
  • Panic disorder is a key focus within anxiety disorder research.

Purpose of the Study:

  • To present the current state of knowledge on the genetics of anxiety disorders, with a focus on panic disorder.
  • To detail clinical, molecular genetic, and meta-analyses studies.
  • To review imaging genetic and pharmacogenetic findings.

Main Methods:

  • Review of clinical and molecular genetic studies.
  • Analysis of gene-environment interactions.
  • Meta-analyses of single association studies.

More Related Videos

In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

Related Experiment Videos

Last Updated: Jun 4, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

In Vivo Modeling of the Morbid Human Genome using Danio rerio
12:31

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
08:22

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations

Published on: December 1, 2017

  • Integration of neuroimaging (fMRI, PET) with genetic data.
  • Examination of pharmacogenetic studies.

    • Main Results:

    • Robust findings implicate genes in serotonergic, noradrenergic, and dopaminergic systems, including the catechol-O-methyltransferase (COMT) gene.
    • The adenosine receptor 2A (A2A) gene shows association with panic disorder and anxiety levels post-caffeine.
    • First imaging genetic findings in panic disorder and social phobia are presented.
    • Pharmacogenetic studies offer insights into treatment.

    Conclusions:

    • Genetic factors are crucial in the multifactorial etiology of anxiety disorders, especially panic disorder.
    • Gene-environment interactions and intermediate phenotypes are vital for understanding complex genetic disorders.
    • Future research directions include advanced imaging genetics and pharmacogenetics.