[Architectonics of gastrointestinal microbial community]

Architectonics of gastrointestinal microbial community in colonic mucosa and feces was studied in patients with different gastrointestinal pathologies and without them. The study model was comprised of Bifidobacteria, Lactobacteria, E.coli, Enterococci, Staphylococci, and Candida. Communities of mucosal and fecal microbes appear to be organized in a definite manner, with most microorganisms forming either indigenous or indigenous-transient associations. Multicomponent indigenous-transient associations prevail in fecal communities, few-component indigenous one or individual microbes in parietal colonic mucin. The structure of community from colonic mucosa overlying a tumour proved identical with that from the apparently normal tissue whereas the community from an inflammed site was structurally closer to the fecal one.