Related Experiment Video
Updated: Jun 4, 2026

Exploring Infant Sensitivity to Visual Language using Eye Tracking and the Preferential Looking Paradigm
Published on: May 15, 2019
The effect of cleft lip on cognitive development in school-aged children: a paradigm for examining sensitive period
Françoise Hentges1, Jonathan Hill, Dorothy V M Bishop
1University of Reading, Reading, Berkshire, UK.
Insights
Children with cleft lip, especially those with late surgical repair, show lasting cognitive deficits. Early mother-infant interactions are crucial for cognitive development, highlighting the need for supportive interventions.
Area of Science:
- Pediatric surgery
- Developmental psychology
- Child health
Background:
- Late surgical repair in infants with cleft lip is linked to poorer cognitive development.
- Early mother-infant interactions mediate these cognitive differences.
- This study investigates the persistence of these effects into later childhood.
Purpose of the Study:
- To determine if cognitive deficits in children with cleft lip persist into later childhood.
- To examine the long-term impact of early surgical repair timing on cognitive outcomes.
- To further investigate the role of early mother-infant interactions in mediating cognitive development.
Main Methods:
- A longitudinal study followed 93 children with cleft lip (early and late repair groups) and 77 controls.
- Cognitive development was assessed at 7 years, including IQ, language, and school achievements.
- Maternal sensitivity at 2 months was analyzed as a mediating factor.
Main Results:
- Children with cleft lip, particularly those with late repair, exhibited significantly lower cognitive development scores.
- Differences in Verbal IQ were mediated by maternal sensitivity at 2 months.
- Maternal sensitivity was a significant predictor of 7-year Verbal IQ, independent of later interactions.
Conclusions:
- Early social interactions in infancy are critically important for child cognitive development.
- Interventions for infants with cleft lip should prioritize and support optimal parental care during infancy.
- Fostering positive early interactions may mitigate long-term cognitive challenges.
Background:
Our previous investigation showed that infants with cleft lip who had undergone late (three-month) surgical repair (but not those with early, neonatal, repair) had significantly poorer cognitive development at 18 months than a group of unaffected control children. These differences were mediated by the quality of early mother-infant interactions. The present study examined whether this pattern persisted into later childhood.
Method:
At 7 years, 93 index (44 early, and 49 late repair) and 77 control children were followed up and their cognitive development assessed (IQ, language and school achievements).
Results:
Index children (particularly those with late lip repair) scored significantly lower than controls on tests of cognitive development. Group differences in Verbal IQ were mediated by 2 months' maternal sensitivity; this was associated with 7-year Verbal IQ, even after controlling for later mother-child interactions.
Conclusions:
Social interactions in the first few months may be of especial importance for child cognitive development. Interventions for infants with cleft lip should be directed at fostering the best possible parental care in infancy.
More Related Videos
Related Concept Videos
Language and Cognition
Cognitive Development During Adolescence
Information Processing Approach
Language Development
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
The Nativist Approach
Cognitivism
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process information is...

