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Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
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Brain morphometry changes and depressive symptoms after traumatic brain injury

Anne Hudak1, Matthew Warner, Carlos Marquez de la Plata

  • 1Dept. of Physical Medicine and Rehabilitation, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9055, USA. Anne.Hudak@utsouthwestern.edu

Psychiatry Research
|February 12, 2011
PubMed
Summary

Traumatic brain injury (TBI) can lead to depression. This study found that atrophy in specific brain regions, including the anterior cingulate and orbitofrontal cortex, correlated with depressive symptoms after TBI.

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Traumatic Brain Injury l: Introduction01:28

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DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...