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Related Concept Videos

Cancer Cell Migration through Invadopodia01:35

Cancer Cell Migration through Invadopodia

Invadosome is a broad category of cell surface structures with proteolytic activity that  degrades the extracellular matrix (ECM). Invadosomes are present in normal cell types, including macrophages, endothelial cells, and neurons, as well as tumor cells. Although the macrophage podosomes and tumor cell invadopodia are classified as invadosomes, they have different structures, molecular pathways, and functions. Podosomes are short structures that last for a few minutes. However, invadopodia can...
Metastasis02:30

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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Related Experiment Video

Updated: Jun 4, 2026

Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional (3D) Model
08:08

Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional (3D) Model

Published on: June 11, 2014

Invasive breast cancer

Robert W Carlson1, D Craig Allred, Benjamin O Anderson

  • 1Stanford Comprehensive Cancer Center, USA.

Journal of the National Comprehensive Cancer Network : JNCCN
|February 12, 2011
PubMed
Summary

No abstract available in PubMed .

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