Related Experiment Videos
[Clinical features and prognosis analysis of small-cell lung cancer complicated with hyponatremia]
Fang Ma1, Xianling Liu, Chunhong Hu
1Department of Medical Oncology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Objective:
To evaluate the clinical features and prognosis of small-cell lung cancer (SCLC) complicated with hyponatremia.
Methods:
The clinical data of 158 patients with SCLC of the Second Xiangya Hospital from January 2000 to December 2007 were studied retrospectively.
Results:
The incidence rate of hyponatremia in SCLC was 42.4%(67/158). The median survival time was 7.6 months in patients with subnormal serum sodium, and 14.1 months in patients with normal values. There was significantly different between 2 groups (P<0.001). The patients who did not fully regain normal values of serum sodium, had poorer survival (6.2 months) compared with the patients with normal serum sodium (10.3 months, P=0.044).
Conclusion:
The incidence rate of hyponatremia in SCLC is high. The prognosis of SCLC with hyponatremia is very poor, especially in those who can not regain normal values of serum sodium after the treatment. So diagnosis and treatment at early stage are very important.
Related Concept Videos
Nephrotic Syndrome III : Nursing Management
Nephrotic Syndrome II : Assessment and Medical Management
Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Chronic Kidney Disease II: Clinical Manifestations
Hypertension III: Clinical Manifestations and Diagnostic Studies
Nephrotic Syndrome I : Introduction