Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Symptom specificity in patients with panic.

P Lelliott1, C Bass

  • 1Greenwich District Hospital, Vanbrugh Hill, London.

The British Journal of Psychiatry : the Journal of Mental Science
|October 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-site validation of an AI-based biomarker test for determining ER, PR, and HER2 status from H&E-stained breast cancer slides.

ESMO real world data and digital oncology·2026
Same author

Differentially spliced mitochondrial CYP419A1 contributes to ethiprole resistance in Nilaparvata lugens.

Insect biochemistry and molecular biology·2025
Same author

Socio-economic factors related to premature death from colorectal cancer in Santiago de Chile, 2014-2018: a cross-sectional study.

Public health·2024
Same author

Beam-Target Helicity Asymmetry for γ[over →]n[over →]→π^{-}p in the N^{*} Resonance Region.

Physical review letters·2017
Same author

SU-D-217A-04: Evaluation of the Spatial Concordance Between the Intratumoral Patterns of 18F-FLT and 18F-FDG Uptake in a Small Animal Tumor Model.

Medical physics·2017
Same author

Use of the synergist piperonyl butoxide can slow the development of alpha-cypermethrin resistance in the whitefly Bemisia tabaci.

Insect molecular biology·2016
Same journal

The pressurised leaky funnel: rethinking recruitment, selection and retention in the UK psychiatry workforce.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Cutting through stigma: psychiatry and neurosurgery working together.

The British journal of psychiatry : the journal of mental science·2026
Same journal

A fourth pillar for evidence-based medicine: implications for psychiatry - CORRIGENDUM.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Understanding negative perceptions of psychiatrists on social media: lessons from public discourse and professional self-reflection.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Attachment-informed psychopharmacology in psychiatric care.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Acceptability and accuracy of point-of-care monitoring of lithium levels.

The British journal of psychiatry : the journal of mental science·2026
See all related articles

Patients with panic disorder (PD) show symptom heterogeneity. Cardiorespiratory (CR) symptom patients experienced more distress during phobia talk and hyperventilation than gastrointestinal (GI) symptom patients.

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Behavioral Medicine

Background:

  • Panic disorder (PD) is characterized by recurrent, unexpected panic attacks.
  • Symptom presentation in PD can vary, with some patients predominantly experiencing cardiorespiratory (CR) symptoms and others gastrointestinal (GI) symptoms.

Purpose of the Study:

  • To investigate the differential response to phobic stimuli and hyperventilation in PD patients with predominantly CR versus GI symptoms.
  • To explore the heterogeneity of panic disorder based on symptom presentation.

Main Methods:

  • Comparison of 13 CR-predominant PD patients with 7 GI-predominant PD patients.
  • Experimental procedure involving exposure to phobia talk and voluntary hyperventilation (VHV).
  • Assessment of anxiety levels, pCO2, respiratory and physical symptoms, and subjective unpleasantness of VHV.

Related Experiment Videos

Main Results:

  • CR patients exhibited higher baseline anxiety than GI patients.
  • During phobia talk, CR patients showed a greater decrease in pCO2 and reported more respiratory symptoms.
  • CR patients found VHV more unpleasant and more similar to their panic attacks, reporting more physical symptoms post-VHV.

Conclusions:

  • Panic disorder is heterogeneous, with distinct symptom clusters (CR vs. GI).
  • Provoking arousal in a system central to a patient's complaints leads to greater distress.
  • Findings challenge the notion of panic disorder as a uniform illness, suggesting tailored treatment approaches may be beneficial.