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Updated: Jun 4, 2026

Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats
Published on: July 5, 2024
[The role of ischemic-reperfusion syndrome in critical state pathology]
Abstract:
Pathogenetic parameters of abdominal and mesenchymal sepsis, traumatic and burn shock, acute pancreatits, ischemic-reperfusion syndrome by renal transplantation, blood flow restoration by reconstructive cardiac surgery, critical limb ischemia in patients with obstructive vessel diseases etc., such as endotoxicosis, cytokinemia, biochemic changes, laser Doppler flowmetry indexes and morphologic signs of tissue necrosis were analyzed. The study proved the pathophisiological universatility of ischemic-reperfusion syndrome as a generated evolutionally and genetically encoded response to superagression, such as iatrogenic blood flow restoration.
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