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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

[Efficacy of cytoflavin in patients in the acute ischemic stroke]

M M Odinak, V I Skvortsova, I A Vozniuk

    Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
    |February 12, 2011
    PubMed

    Insights

    Cytoflavin shows potential in treating acute ischemic stroke by reducing neurological deficits and improving daily living activities. This suggests it may help preserve brain tissue during the critical acute phase.

    Area of Science:

    • Neurology
    • Pharmacology

    Context:

    • Acute ischemic stroke is a leading cause of long-term disability.
    • Effective treatments are needed to improve patient outcomes and reduce brain damage.

    Purpose:

    • To evaluate the efficacy of cytoflavin in patients with acute ischemic stroke.
    • To assess the impact of cytoflavin on neurological deficit and daily living activities.
    • To investigate cytoflavin's effect on preserving brain matter using MRI.

    Summary:

    • A multicenter study involving 70 patients investigated cytoflavin's efficacy in acute ischemic stroke.
    • Patients received standard therapy; the main group additionally received cytoflavin intravenously and orally.
    • Assessments included neurological scales (NIHSS, Rankin, Barthel) and MRI to measure lesion volume and brain matter preservation.

    Impact:

    • Cytoflavin demonstrated a trend towards preserving brain matter in the acute phase of stroke.
    • Treatment with cytoflavin was associated with reduced neurological deficits.
    • Improved activities of daily living were observed in patients treated with cytoflavin, potentially due to less brain damage.

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