Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Cancer Prevention

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Relative Risk

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...

The Retinoblastoma Gene

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Plasma enterolactone and risk of prostate cancer in middle-aged Swedish men.

European journal of nutrition·2017

Same author

Absorption of plant lignans from cereals in an experimental pig model.

The British journal of nutrition·2016

Same author

Longitudinal biobanks-based study on the joint effects of infections, nutrition and hormones on risk of prostate cancer.

Acta oncologica (Stockholm, Sweden)·2016

Same author

Alkylresorcinol metabolites in urine and plasma as potential biomarkers of rye and wheat fiber consumption in prostate cancer patients and controls.

Nutrition and cancer·2015

Same author

Responsiveness of urinary and plasma alkylresorcinol metabolites to rye intake in finnish women.

Cancers·2013

Same author

Plasma alkylresorcinol metabolites as biomarkers for whole-grain intake and their association with prostate cancer: a Swedish nested case-control study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology·2013

Same journal

Investigations of a multi-objective diet optimization model including human health, environment, and observed dietary intake.

Food & nutrition research·2026

Same journal

Maternal cafeteria diet and methyl donor supplementation modulate gut microbiota and anxiety-like behavior in male offspring.

Food & nutrition research·2026

Same journal

Maternal and infant serum ferritin concentrations across pregnancy and postpartum: a longitudinal study in Norway.

Food & nutrition research·2026

Same journal

Influence of diet on the modulation of gut microbiota and its neurobiological effects on cognition: a systematic review and meta-analysis.

Food & nutrition research·2026

Same journal

Usual nutrient intake and adherence to dietary reference values among 3-6-year-old Finnish preschoolers.

Food & nutrition research·2026

Same journal

Effects of SRW<sup>®</sup> Stem on the functional properties, oxidative stress and inflammation of human umbilical cord mesenchymal stem cells.

Food & nutrition research·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 4, 2026

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Published on: October 16, 2010

Can rye intake decrease risk of human breast cancer?

Herman Adlercreutz¹

¹Institute for Preventive Medicine, Nutrition and Cancer, Folkhälsan Research Center and Division of Clinical Chemistry, Biomedicum, University of Helsinki, Helsinki, Finland.

Food & Nutrition Research

|February 12, 2011

Summary

This summary is machine-generated.

Whole grain rye products may reduce breast cancer (BC) risk. Rye

Keywords:

alkylresorcinols fibre lignans oestrogens wholegrain

More Related Videos

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration

Published on: June 9, 2023

X-ray Visualization of Intraductal Ethanol-based Ablative Infusion for Prevention of Breast Cancer in Rabbit Models

X-ray Visualization of Intraductal Ethanol-based Ablative Infusion for Prevention of Breast Cancer in Rabbit Models

Published on: September 12, 2025

Related Experiment Videos

Last Updated: Jun 4, 2026

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Published on: October 16, 2010

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration

Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration

Published on: June 9, 2023

X-ray Visualization of Intraductal Ethanol-based Ablative Infusion for Prevention of Breast Cancer in Rabbit Models

X-ray Visualization of Intraductal Ethanol-based Ablative Infusion for Prevention of Breast Cancer in Rabbit Models

Published on: September 12, 2025

Area of Science:

Nutrition Science
Oncology
Food Science

Background:

Rye is rich in fiber and bioactive compounds, potentially offering protection against breast cancer (BC).
Dietary fiber and specific rye components are investigated for their role in BC prevention.

Purpose of the Study:

To review existing evidence and theoretical frameworks supporting rye's role in BC prevention.
To explore mechanisms by which rye components may inhibit BC development.

Main Methods:

A literature review focusing on Nordic research.
Analysis of scientific literature on rye's composition and health effects.

Main Results:

Rye fiber fermentation influences bile acid metabolism, potentially reducing toxicity.
Rye fiber can lower plasma estrogen concentrations by reducing enterohepatic circulation.
Bioactive compounds in rye, including lignans and alkylresorcinols, possess antioxidant and anticarcinogenic properties.
Vitamins, minerals, and phytic acid in rye may also contribute to BC protection.

Conclusions:

Whole grain rye products are likely beneficial in reducing breast cancer risk.
Further research into rye's chemopreventive potential is warranted.